Folic Acid

What It Is
Folic acid is a water-soluble vitamin known by many other names--vitamin B9, folate, folacin, and tetrahydrofolic acid. It is available in fresh leafy green vegetables and liver. Folic acid is also manufactured synthetically and is included in most multivitamin supplements. An injectable form is available by prescription.

What It Does
Folic acid is essential for the formation of the DNA that makes up our genes and the RNA that transmits their instructions. It is particularly important in the body's production of red blood cells. Folic acid deficiency results in megaloblastic anemia, an anemia similar to that caused by vitamin B12 deficiency. Symptoms include weight loss, digestive problems, and a burning feeling in the tongue.

Why You Need It
Folic acid helps us grow and develop normally. It also regulates nerve cell development in the embryo and the developing baby. Folic acid supplements are used to treat the anemia that may occur with alcoholism, liver disease, pregnancy, breastfeeding, or the use of oral contraceptives.

Can You Take Too Much?
Very high amounts of folic acid have been taken over long periods of time without any adverse effects. However, there is a chance that prolonged use of large amounts might lead to the formation of folacin crystals in the kidneys or cause severe neurologic problems. Symptoms such as loss of appetite, nausea, gas, and abdominal bloating may occur if you take more than 1,500 micrograms of folic acid per day.

Recommended Daily Allowances
ADULTS

For everyone 11 years and older the official recommended dietary allowance is 400 micrograms.

Women need an additional 400 micrograms of folic acid each day during pregnancy. (It is believed that folic acid supplementation during pregnancy may prevent the development of neural tube defects that can lead to mental retardation.) Breastfeeding mothers need an extra 100 micrograms of folic acid per day.

   Many others may also require additional folic acid. People who do not eat a well-balanced diet, those over the age of 55, people who abuse alcohol or other drugs, and women who take oral contraceptives should discuss the need for folic acid supplementation with their physicians.


CHILDREN
Infants up to 6 months: 30 micrograms
Ages 6 to 12 months: 45 micrograms
Ages 1 to 3 years: 100 micrograms
Ages 4 to 6 years: 200 micrograms
Ages 7 to 10 years: 300 micrograms

Best Dietary Sources
Folic acid is available in green leafy vegetables such as broccoli, spinach, and romaine lettuce. It is important to note that cooking these vegetables reduces the amount of folic acid the body receives. Other natural sources of folic acid include: fruits--especially oranges and orange juice--calves' liver, brewer's yeast, wheat germ, rice, barley, beans, peas, split peas, chickpeas, lentils, soybeans, and sprouts.

   One-half pound of fresh spinach contains 463 micrograms of folic acid; 1 tablespoon of brewer's yeast provides 308 micrograms. One-half cup of dry soybeans has 236 micrograms of folic acid; 1 cup of fresh orange juice provides 164 micrograms.

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Revised: June 10, 2006 .