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Scientifically Burning Off
Excess Fat
The process of producing energy from stored reserves, thermogenesis
, is one of the primary means by which we burn fat. It can be stimulated by
food, cold exposure , or exercise. Our bodies contain two types of fat cells:
metabolically active brown fat is a major site of thermogenesis, comprising
approximately 1% of the body mass, and the metabolically inactive white fat
which functions primarily as fat storage. Brown fat cells contain an abundance
of sympathetic nerve fibers which can release the neurotransmitter
norepinephrine. Norepinephrine triggers thermogenesis and activates
triglyceride lipase, thus breaking down the fat stored in inactive white fat
cells and allowing it to be burned for energy.
Chronic or "yo-yo" dieting may permanently
impair the ability of brown fat to respond to norepinephrine, and consequently
lower the level of thermogenesis, making weight loss difficult if not
impossible. Decreased thermogenesis not only discourages the body from burning
fat, but creates an increased appetite as well, usually resulting in increased
weight gain. (References 1, 2, 3, 4)
Ma Huang (Ephedra)
The branching shrub Ma Huang (Ephedra sinica)
includes weight reduction among its many therapeutic uses. One of the active
ingredients in this plant, ephedrine, is able to directly stimulate beta
receptors on the fat cells, activating thermogenesis, burning stored fat and
generating energy (Reference 5).
A four month study using ten women who had been chronic
dieters, and were on 1000-1400 kcal/day diet demonstrated that weight loss was
four times greater during the ephedrine trial than when a placebo was given.
No major adverse health effects were reported by any of the subjects, although
during the first month a few individuals reported mild insomnia, agitation,
palpitation and giddiness (Reference 6). Other studies have shown that the
weight-loss effects of ephedrine are enhanced with other herbal substances
such as methylxanthines, caffeine, theophylline, (References 7, 8) and
salicylates (Reference 9).
Willow (Salix)
Bark of the willow species contains salicin, a naturally
occurring salicylate (aspirin is a commonly-used synthetic form of
salicylate). In laboratory studies, salicylates doubled the effect of
ephedrine alone. Long-term administration of the salicylate alone had no
effect on body composition (Reference 9). Without Ma Huang, willow is
ineffective, but together the herbs produce a high-performance weight loss
effect.

Link
to Enrich's Official Statement on Ephedra

Ephedra is contraindicated in patients with most
forms of cardiovascular disease, tachycardia, hypertension, hyperthyroidism,
pheochromocytoma, closed angle glaucoma, men who have difficulty urinating due
to an enlarged prostate or pregnant women (Reference 10). Patients taking
antihypertensive or antidepressant medication should also avoid taking Ephedra.
Ephedra taken in high doses may cause adverse reactions including tachycardia
and dry mouth. These side effects can be avoided if the patient is started at a
low dose and gradually increases his intake over the first week. If a reaction
still occurs, cutting back the intake slightly will eliminate any discomfort.

The U.S. Food and Drug Administration has not evaluated this
page's information. The products described are intended solely as food
supplements to enhance general health, and are not intended to diagnose, treat,
cure, or prevent any disease. Nothing listed here should be considered as
medical advice for dealing with a given problem. You should consult your health
care professional for individual guidance for specific health problems.

FDA intends to publish a rule in the
coming weeks that finds that dietary supplements containing ephedrine alkaloids
present an unreasonable risk of illness or injury under conditions of use
recommended or suggested in the labeling of the product, or, if no conditions of
use are suggested in the labeling, under ordinary conditions of use, and are
therefore adulterated under Section 402(f)(1)(A) of the Federal Food, Drug, and
Cosmetic Act (the Act). This rule will become effective 60 days after
publication so as to allow for congressional review in accordance with 5 U.S.C.
801-808. You can find the Act and its implementing regulations through links on
FDA's Internet home page at
www.fda.gov.

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